Five years ago, Harry and Sally shared a car from the University of Chicago to New York City together. They didn’t know each other that well; Harry was dating Sally’s friend Amanda. They didn’t exactly hit it off; Harry completely annoyed Sally, and when he propositioned her, she refused. He insisted that men and women can never be friends because there is always sexual tension between them. They went their separate ways, but now, five years later, Harry recognizes Sally’s boyfriend Joe as he’s dropping Sally off at the airport, and later, on the plane, he strikes up a conversation.